SpatioScript: LLM-Powered Spatial Biology Query Tool

Overview

SpatioScript is an LLM-powered spatial biology query tool that lets users ask natural language questions about spatial and single-cell datasets. The system connects preprocessed data, cell type annotations, spatial graphs and image views to answer biologically meaningful questions.

Key Features

• •Built an end-to-end prototype that turns English questions into queries over spatial biology data.
• •Combined Scanpy/anndata workflows with Neo4j graphs and OpenCV-based image handling.
• •Integrated OpenAI's API to interpret questions and route them to the right data structures.
• •Focused on use cases such as neighborhood enrichment, tumor microenvironment questions and marker discovery.

Technologies

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